Explores interdisciplinary and transdisciplinary approaches to understanding and activating music’s power to influence health and well-being. Offers students an opportunity to obtain the analytical tools required to understand, synthesize, and critique empirical research investigations; evaluate research design, models, and outcomes; and identify future research directions and applications of music-in-health research in music therapy, music medicine, psychology, neuroscience, public health, and medical ethnomusicology. At the population level, discusses music as a health promotion tool and social determinant of health and music access as a health equity issue. Emphasizes diverse approaches across disciplines and cultures to advance physiological, psychological, social, and spiritual health through music. Through self-experimentation and critical reflection, offers hands-on experience with multiple modes of investigation to develop personalized music-based resource toolkits to support well-being.