CHEM 5648 — Chemical Principles and Application of Drug Metabolism and Pharmacokinetics
3 semester hoursGraduateLectureusually offered: springtypical days: WBostonTraditional
Offers students an opportunity to obtain a comprehensive grounding in the chemistry of drug metabolism and pharmacokinetics (DMPK) and its application to drug design and optimization. Multiple rounds of chemical synthesis and testing are usually required to discover new drugs with the appropriate balance of properties such as potency and selectivity, efficacy in preclinical models of disease, safety, and pharmacokinetics. Introduces students to modern tools and concepts utilized to screen for favorable DMPK properties, as well as methods to predict human PK from in vitro and preclinical data. Examines the linkage between drug levels in the body, pharmacodynamic response (PK/PD), and drug-drug interactions in the context of the iterative process of chemical drug synthesis.
Offering history
| Term | Sections | Enrolled | Capacity | Full | Open seats/section |
|---|---|---|---|---|---|
| Spring 2024 | 1 | 34 | 35 | 97% | 1.0 |
| Spring 2025 | 1 | 35 | 35 | 100% | 0.0 |
| Spring 2026 | 1 | 25 | 30 | 83% | 5.0 |
Snapshots from scheduled scrapes — not live seat availability. "Full" can exceed 100% when sections over-enroll.
Meeting times
Share of recent sections by weekday: M 0% · T 0% · W 100% · Th 0% · F 0%
Common patterns: W (100% of sections) — in patterns, R means Thursday
Professors
Spring
- Iain Martin (100% of students) · reviews
Percentages are each professor's average share of the season's enrolled students in recent terms.
Links
Official catalog (CHEM course descriptions) · Student reviews on RateMyHusky · All CHEM courses · Plan it at numap.app